# VYRSA™ Technologies

> VYRSA Technologies was a Pennsylvania medical-device company built around minimally invasive sacroiliac joint fusion. Its portfolio gave physicians three procedural choices - the integrated-anchor V1 implant, the posterior allograft Pro system, and compressive Fix screws - before Nevro acquired the company in November 2023 for $40 million upfront and up to $35 million in milestones. Nevro rebranded the products as Nevro1, NevroPro, and NevroFix; Globus Medical then acquired Nevro in April 2025.

- **Founded:** 2021
- **Headquarters:** King of Prussia, United States
- **Founders:** Daniel A. Pontecorvo (Co-founder and CEO), Terry Harvey (Founder, creator, president and co-CEO)
- **Team size:** LinkedIn listed 11-50 employees before acquisition; supplied contact data lists 2 employees, so the exact standalone headcount is uncertain.
- **Products:** VYRSA V1™ / Nevro1™ SI Joint Fusion System, VYRSA Pro™ / NevroPro™, VYRSA Fix™ / NevroFix™, Physician education and procedural support
- **Notable:** Founded in 2021 and acquired by Nevro on November 30, 2023, before its third anniversary., Launched the VYRSA V1 SI Fusion System after FDA 510(k) clearance of the underlying Camber SI system in 2022., Built a portfolio spanning posterior integrated transfixation, posterior allograft, and lateral screw approaches.

## Products & services

- **VYRSA V1™ / Nevro1™ SI Joint Fusion System** — A posterior minimally invasive 3D-printed titanium cage with porous surfaces and integrated deployable anchors that transfix the ilium and sacrum for immediate stabilization and potential long-term fusion.
- **VYRSA Pro™ / NevroPro™** — A cortical allograft SI-fusion system designed for a posterior inferior-inlet approach, joint decortication, fusion-bed preparation, and multiple patient anatomies.
- **VYRSA Fix™ / NevroFix™** — 3D-printed titanium lateral fixation screws designed to compress and stabilize the SI joint as an adjunct to fusion.
- **Physician education and procedural support** — Training, surgical technique guidance, and product support for physicians adopting the SI-joint fusion portfolio; Nevro reported more than 220 physicians participated in training sessions year-to-date by May 2024.

## Achievements

- Founded in 2021 and acquired by Nevro on November 30, 2023, before its third anniversary.
- Launched the VYRSA V1 SI Fusion System after FDA 510(k) clearance of the underlying Camber SI system in 2022.
- Built a portfolio spanning posterior integrated transfixation, posterior allograft, and lateral screw approaches.
- Received a February 2024 FDA 510(k) clearance that allowed the integrated Nevro1 implant to be used without a supplemental fixation screw.
- Published a 2024 cadaveric biomechanical and computational comparison reporting motion reduction equivalent to a lateral triangular-rod system across all tested planes, with less bone removal and more modeled fusion surface area than compared approaches.
- Transferred two issued US patents and one pending US patent application to Nevro; the acquisition also included access to licensed Camber patent rights.
- Attracted an acquisition price of $40 million upfront with up to $35 million in development and sales milestones.

## Latest updates

- **2023-11** — Nevro acquired VYRSA for $40 million at closing and up to $35 million in contingent development and sales payments.
- **2024-02** — The FDA cleared the Camber SI Fixation System under K233972, enabling Nevro1 to be marketed without a supplemental lateral fixation screw.
- **2024-05** — Nevro said more than 220 physicians had participated in SI-joint fusion training sessions year-to-date as it prepared a broader market release.
- **2024-10** — A peer-reviewed cadaveric biomechanical and computational comparison of the integrated posterior transfixation approach was published in Medical Devices: Evidence and Research.
- **2025-04** — Globus Medical completed its acquisition of Nevro, making Nevro a wholly owned subsidiary and moving the former VYRSA portfolio into Globus.

## Links

- Website: https://www.vyrsatech.com/
- LinkedIn: https://www.linkedin.com/company/vyrsa
- Instagram: https://www.instagram.com/vyrsaspine/

---

Profile page: https://yespress.io/vyrsa-technologies
Published by YesPress — https://yespress.io
Last updated: 2026-08-22