# Subtle Medical

> Subtle Medical is a Stanford-born AI company that makes regular MRI and PET scanners faster and sharper through deep learning denoising and image enhancement software. Its FDA-cleared, vendor-neutral products - including SubtlePET, SubtleMR/SubtleHD, SubtleSYNTH and AiMIFY - help radiology departments shorten scan times, reduce contrast dose, and increase patient throughput without buying new hardware.

- **Founded:** 2017
- **Headquarters:** Menlo Park, California, United States
- **Founders:** Enhao Gong (Founder & CEO), Greg Zaharchuk (Co-founder; Neuroradiologist, Stanford Professor)
- **Team size:** ~69 employees
- **Products:** SubtlePET, SubtleMR / SubtleHD, SubtleSYNTH, AiMIFY, Subtle-ELITE
- **Notable:** First AI software to receive FDA clearance for nuclear medicine image enhancement (SubtlePET, 2018)., Named one of TIME's World's Top HealthTech Companies (2025)., FDA clearance for SubtleHD - industry-leading MRI acceleration software (February 2025).

## Products & services

- **SubtlePET** — FDA-cleared AI software that denoises PET images, enabling up to 4x faster PET scans and lower radiotracer doses.
- **SubtleMR / SubtleHD** — FDA-cleared MRI enhancement and acceleration software using denoising and resolution enhancement to make scans up to 80% faster while maintaining image quality.
- **SubtleSYNTH** — FDA-cleared AI for synthetic imaging - generating additional MR contrasts (like STIR) from existing sequences.
- **AiMIFY** — AI contrast-enhancement software co-developed with Bracco that boosts contrast signal, opening the door to lower gadolinium doses.
- **Subtle-ELITE** — Bundled suite combining acceleration, enhancement, and workflow tools for health systems.

## Achievements

- First AI software to receive FDA clearance for nuclear medicine image enhancement (SubtlePET, 2018).
- Named one of TIME's World's Top HealthTech Companies (2025).
- FDA clearance for SubtleHD - industry-leading MRI acceleration software (February 2025).
- Multiple NIH grants supporting synthetic imaging research.
- Over 600 US installations and 1,000+ globally.

## Latest updates

- **2025-11** — Announced 2.5x annualized US revenue growth and new partnerships at RSNA 2025.
- **2025-02** — FDA clearance for SubtleHD.
- **2024-11** — Unveiled Subtle-ELITE bundled suite at RSNA 2024.
- **2024-09** — NIH SBIR Phase II funding for SubtleSYNTH expansion to brain imaging.

## Links

- Website: https://subtlemedical.com
- LinkedIn: https://www.linkedin.com/company/subtlemedical
- Twitter/X: https://twitter.com/SubtleMedical
- YouTube: https://www.youtube.com/@SubtleMedical

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Profile page: https://yespress.io/subtle-medical
Published by YesPress — https://yespress.io
Last updated: 2026-05-18