# Scott Kokones

> Scott Kokones is co-founder and CEO of Enspire DBS Therapy, a Cleveland Clinic portfolio company building an implantable deep brain stimulation system paired with physical rehab to restore arm function in stroke survivors. He is running the RESTORE pivotal trial after the EDEN proof-of-concept study, having raised $27.9M total including a $17.6M Series B in 2023 and a $10.3M Series B1 in January 2026. Alongside Enspire he is a general partner at Guide Medical Ventures and a co-founder of Qr8 Health and CardioSolv Ablation Technologies. His earlier career runs through Intelect Medical, Boston Scientific, Enpath Medical, and Medtronic.

- **Role:** CEO and Co-Founder at Enspire DBS Therapy, Inc.
- **Organizations:** Enspire DBS Therapy, Inc., Guide Medical Ventures, Qr8 Health, CardioSolv Ablation Technologies, Intelect Medical, Boston Scientific, Enpath Medical, Medtronic
- **Nationality:** American
- **Education:** BS, Mechanical Engineering, University of Michigan, MBA, Boston University
- **Known for:** Co-founded and leads Enspire DBS Therapy, a Cleveland Clinic portfolio company, Raised $27.9M in cumulative funding for Enspire DBS, Advanced the EDEN first-in-human proof-of-concept trial at Cleveland Clinic

## Career timeline

- **early career** — Engineering and product roles at Medtronic and Enpath Medical
- **mid career** — Roles at Boston Scientific and Intelect Medical in neuromodulation
- **2010** — Co-founded Enspire DBS Therapy in Cleveland
- **2011** — Co-founded Guide Medical Ventures, a medical device venture firm
- **2013** — Co-founded CardioSolv Ablation Technologies
- **2014** — Took CEO title at Enspire DBS Therapy
- **2017** — Co-founded Qr8 Health, a digital health company for neurological outcome assessments
- **2023** — Enspire DBS closed a $17.6M Series B led by Cleveland Clinic with JobsOhio Growth Capital
- **2026** — Enspire DBS closed a $10.3M Series B1 led by Genesys Capital in January

## Achievements

- Co-founded and leads Enspire DBS Therapy, a Cleveland Clinic portfolio company
- Raised $27.9M in cumulative funding for Enspire DBS
- Advanced the EDEN first-in-human proof-of-concept trial at Cleveland Clinic
- Launched the RESTORE pivotal clinical trial for DBS + rehab in chronic stroke
- Co-founder of three medical device or digital health companies plus a venture firm

## Latest updates

- **2026-01** — Closed $10.3M Series B1 led by Genesys Capital; Jamie Stiff joined the board
- **2023-08** — Closed $17.6M Series B led by Cleveland Clinic and JobsOhio Growth Capital

## Links

- Website: https://enspiredbs.com
- LinkedIn: https://www.linkedin.com/in/scott-kokones-4275b55/

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Profile page: https://yespress.io/scott-kokones
Published by YesPress — https://yespress.io
Last updated: 2026-07-08