# Reshma Khilnani

> Reshma Khilnani is the Co-Founder and CEO of Medplum, an open-source, FHIR-native healthcare developer platform that gives builders the infrastructure to create custom EHRs, patient portals, and clinical apps without starting from scratch. A three-time founder with exits to Box and Ro, she previously built MedXT (YC W13) and Droplet Health before returning to Y Combinator as a Visiting Group Partner and then launching Medplum in the S22 batch. An MIT computer science graduate with deep expertise in healthcare regulation and payments infrastructure, she is one of the most technically fluent CEOs in digital health.

- **Role:** Co-Founder and CEO at Medplum
- **Organizations:** Medplum, Y Combinator, Box, Facebook, MedXT, Droplet Health, Microsoft
- **Nationality:** American
- **Education:** B.S. in Computer Science, Massachusetts Institute of Technology (MIT), Masters of Engineering (MEng) in EECS, Massachusetts Institute of Technology (MIT), Secondary Education, Rishi Valley School
- **Known for:** Three-time founder with two successful exits: MedXT to Box and Droplet Health to Ro, Y Combinator Visiting Group Partner, mentoring 100+ early-stage startups, Founded Medplum (YC S22), the open-source FHIR-native healthcare developer platform

## Career timeline

- **Early career** — Engineer/PM at Microsoft
- **2010-2012** — Product Manager at Facebook, working on Developer Platform, Facebook Credits, Facebook for Android, Facebook Gifts, and global payments network with 80+ payment methods
- **2013** — Co-Founded MedXT (YC W13), a medical imaging platform for telemedicine serving hospitals and clinics worldwide
- **2014** — MedXT acquired by Box
- **2014-2019** — Engineering Manager at Box; led Content Experience team delivering 3D rendering, DICOM, and content preview products; featured in Fortune as part of 'Box's big data triple threat'
- **2019-2021** — Co-Founded and Co-CEO of Droplet Health (at-home diagnostics); acquired by Ro (now Kit.com)
- **2021** — Visiting Group Partner at Y Combinator, mentoring 100+ early-stage startups on product, technology, and regulation
- **2021** — Co-Founded Medplum
- **2022** — Medplum accepted into Y Combinator S22 batch
- **2024** — Medplum achieves $1.2M revenue with 8-person team; 1,500+ GitHub stars; 150+ open source contributors

## Achievements

- Three-time founder with two successful exits: MedXT to Box and Droplet Health to Ro
- Y Combinator Visiting Group Partner, mentoring 100+ early-stage startups
- Founded Medplum (YC S22), the open-source FHIR-native healthcare developer platform
- Medplum reached $1.2M ARR with only 8 employees in 2024
- Grew Medplum's open source community to 1,500+ GitHub stars and 150+ contributors
- Featured in Fortune magazine as one of 'Box's big data triple threat' (2015)
- Published author at TechCrunch
- MIT Computer Science graduate (B.S. and MEng)
- Built Facebook's global payments network supporting 80+ payment methods
- ONC-certified healthcare platform under her leadership at Medplum

## Latest updates

- **2025-01** — Featured in interview as Co-Founder and CEO of Medplum discussing the platform's growth and vision
- **2024-12** — Published Medplum Year in Review 2024 and 2025 Roadmap on the Medplum blog
- **2024-07** — Featured on Digital CxO 'Leadership Insights: Health Care Transformation' video interview
- **2024-06** — Featured on Stack Overflow Podcast discussing how to build open source apps in a highly regulated industry
- **2024-05** — Guest on Digital Health Hackers Podcast Ep.9: 'Building Custom EHRs on FHIR'

## Links

- Website: https://medplum.com
- LinkedIn: https://www.linkedin.com/in/reshmakhilnani
- Twitter/X: https://x.com/reshmakhilnani
- GitHub: https://github.com/reshmakh
- Instagram: https://www.instagram.com/reshmakh/

---

Profile page: https://yespress.io/reshma-khilnani
Published by YesPress — https://yespress.io
Last updated: 2026-05-13