# Prilenia

> Prilenia is a privately held, clinical-stage biopharmaceutical company developing pridopidine, an investigational oral sigma-1 receptor agonist, for Huntington’s disease and ALS. Founded in 2018 by Michael R. Hayden, it operates internationally and partners with Ferrer on development and potential commercialization. Confirmatory Phase 3 studies began in 2026 after earlier trials missed their main endpoints; the drug remains unapproved.

- **Founded:** 2018
- **Headquarters:** Naarden, Netherlands
- **Founders:** Michael R. Hayden (Founder and Chief Executive Officer)
- **Products:** Pridopidine
- **Notable:** Raised a US$62.5 million Series A in 2020 and US$43 million Series B in 2021., Pridopidine holds US and EU orphan designations in HD and ALS, plus FDA Fast Track in HD; these are not approvals., Signed a territorial license and co-development agreement with Ferrer in April 2025.

## Products & services

- **Pridopidine** — Investigational oral sigma-1 receptor agonist in confirmatory Phase 3 development for Huntington’s disease (PRECISE-HD) and ALS (PREVAiLS). Not approved for commercial use.

## Achievements

- Raised a US$62.5 million Series A in 2020 and US$43 million Series B in 2021.
- Pridopidine holds US and EU orphan designations in HD and ALS, plus FDA Fast Track in HD; these are not approvals.
- Signed a territorial license and co-development agreement with Ferrer in April 2025.
- Started confirmatory Phase 3 programs in HD and ALS in 2026.

## Latest updates

- **2026-09** — Appointed Frederick (Rick) E. Munschauer III as Chief Medical Officer on September 8.
- **2026-07** — Announced initiation of PRECISE-HD on July 7, with US recruitment underway.
- **2026-05** — Announced placebo-arm clinical dataset agreement with CHDI on May 26.
- **2026-04** — Appointed Elisabeth Leiderman as Chief Financial Officer on April 28.
- **2026-03** — Announced first participant enrollment in PREVAiLS on March 30.

## Links

- Website: https://prilenia.com/
- LinkedIn: https://www.linkedin.com/company/prilenia
- Twitter/X: https://x.com/PrileniaTx

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Profile page: https://yespress.io/prilenia
Published by YesPress — https://yespress.io
Last updated: 2026-10-03