# Pow.Bio

> Pow.Bio is an Alameda biomanufacturing company that pairs a two-chamber continuous fermentation process with model-driven control software. It helps food, ingredient, chemical and biotechnology companies optimize strains, make test material and transfer processes from laboratory vessels into commercial plants - with the aim of getting more output from smaller or existing equipment.

- **Founded:** 2019
- **Headquarters:** Alameda, United States
- **Founders:** Shannon Hall (Co-founder and CEO), Ouwei Wang (Co-founder and CTO)
- **Products:** Two-chamber continuous fermentation, Cassie, Fermentation as a service, Pow.Bio-Bühler integrated platform
- **Notable:** Transferred a high-value dairy-protein process from 300 liters to 3,000 liters at an external French facility in under ten weeks., Reported 300 hours of stable continuous operation, more than 3x material output and over 50% lower cost of goods versus its fed-batch comparison in the ATV Technologies case study., Opened a 25,000-square-foot FDA-registered food-grade facility in Alameda capable of moving projects from lab work to hundreds of kilograms of finished product.

## Products & services

- **Two-chamber continuous fermentation** — A process that grows fresh biomass in one chamber and feeds it into a separate production chamber, with filtration to harvest product, remove waste and recycle cells and media.
- **Cassie** — Model-predictive control and digital-twin software used to simulate runs, choose settings, monitor production and adjust process variables in real time.
- **Fermentation as a service** — Strain validation, media and process optimization, prototyping, regulatory or market-test material production, scale-up and manufacturing support.
- **Pow.Bio-Bühler integrated platform** — A commercial offering combining Pow.Bio’s continuous process and control software with Bühler’s engineering, installation, commissioning and lifecycle support.

## Achievements

- Transferred a high-value dairy-protein process from 300 liters to 3,000 liters at an external French facility in under ten weeks.
- Reported 300 hours of stable continuous operation, more than 3x material output and over 50% lower cost of goods versus its fed-batch comparison in the ATV Technologies case study.
- Opened a 25,000-square-foot FDA-registered food-grade facility in Alameda capable of moving projects from lab work to hundreds of kilograms of finished product.
- Produced commercial-scale quantities of cell-cultured cocoa with California Cultured in 2025.
- Named a 2026 World Economic Forum Technology Pioneer.

## Latest updates

- **2026-06** — Selected as a World Economic Forum 2026 Technology Pioneer.
- **2025-12** — Announced an integrated continuous precision-fermentation platform with Bühler and opened customer onboarding.
- **2025-11** — Published results from a 3,000-liter external deployment at ATV Technologies: 300 hours, more than 3x material and over 50% lower COGS in the disclosed comparison.
- **2025-04** — Announced commercial-scale food-grade cultured-cocoa production with California Cultured in Alameda.
- **2024-07** — MeliBio reported record bioprocess improvements from its Pow.Bio scale-up collaboration.

## Links

- Website: https://www.pow.bio/
- LinkedIn: https://www.linkedin.com/company/powbio
- Twitter/X: https://twitter.com/powbio
- YouTube: https://www.youtube.com/watch?v=BIMertgu9h8
- Instagram: https://www.instagram.com/pow.bio/
- Facebook: https://facebook.com/pow.bio

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Profile page: https://yespress.io/pow-bio
Published by YesPress — https://yespress.io
Last updated: 2026-09-28