# NVIGEN Inc.

> NVIGEN Inc. is a Sunnyvale, California nanobiotechnology company that engineers multifunctional, biodegradable magnetic and fluorescent nanoparticles for biomedical research, diagnostics and therapeutics. Built on its proprietary nanoparticle-imaging-delivery (NID) and MagVigen platforms, NVIGEN makes reagents and assays that capture DNA, RNA, proteins and rare cells from a single blood or tissue sample - powering liquid biopsy, NGS/multiomics sample preparation, single-cell spatial sequencing, and targeted drug and cell therapy. Its products are used by researchers at more than 40 institutions worldwide.

- **Founded:** 2011
- **Headquarters:** Sunnyvale, California, United States
- **Founders:** Aihua Fu (Co-Founder, President & CEO)
- **Team size:** Approximately 11 employees
- **Products:** MagVigen Magnetic Nanobeads, NVIGEN X, NERNST-Seq, cfDNA / ctDNA Extraction Kits, DNA Size Selection & Cleanup Kits
- **Notable:** Built a proprietary nanoparticle-imaging-delivery (NID) and MagVigen platform protected by 10 issued patents and 18 pending applications., Products used and cited by 40+ research institutions globally., Pioneered high-throughput RNA isolation from single cells within intact tissue (NERNST-Seq), published in peer-reviewed journals.

## Products & services

- **MagVigen Magnetic Nanobeads** — Multifunctional, biodegradable magnetic nanoparticles - the core platform behind NGS sample prep, DNA/RNA/protein capture, cell separation and workflow automation. Protected by 10 issued patents and 18 pending applications.
- **NVIGEN X** — NGS/multiomics precision-medicine biomarker profiling assay that integrates circulating tumor DNA (ctDNA), circulating tumor cells (CTC) and protein biomarkers from a single blood sample for cancer recurrence prediction and therapy guidance.
- **NERNST-Seq** — Nanoparticle-Enhanced RNA Spatial & Temporal Sequencing - high-throughput isolation of RNA from single cells within intact tissue, enabling spatial and temporal single-cell sequencing.
- **cfDNA / ctDNA Extraction Kits** — High-yield circulating free / tumor DNA extraction reagents for liquid biopsy workflows.
- **DNA Size Selection & Cleanup Kits** — Magnetic-bead fragment isolation and cleanup for next-generation sequencing library prep.
- **On-Bead ELISA & Protein Capture Kits** — Bead-based immunoassays and immunoprecipitation reagents for protein biomarker detection and chromatin immunoprecipitation.
- **Cell Capture & Separation Systems** — Rare-cell isolation including circulating tumor cells (CTC) and T-cell activation for immunology and cell therapy.
- **Drug Delivery Nanoparticles** — Biodegradable nanoparticles engineered for in vivo cancer targeting, imaging and targeted drug/cell therapy.

## Achievements

- Built a proprietary nanoparticle-imaging-delivery (NID) and MagVigen platform protected by 10 issued patents and 18 pending applications.
- Products used and cited by 40+ research institutions globally.
- Pioneered high-throughput RNA isolation from single cells within intact tissue (NERNST-Seq), published in peer-reviewed journals.
- Demonstrated highly sensitive, NGS-data-efficient ctDNA testing with NVIGEN X.
- Unveiled a comprehensive multimodal liquid biopsy (ctDNA + CTC + protein) at the San Antonio Breast Cancer Symposium, December 2023.

## Latest updates

- **2023-09** — Announced a breakthrough in high-resolution tissue RNA sequencing using magnetic nanoparticle capture from nanopipette aspiration of single-cell contents.
- **2023-12** — Unveiled comprehensive multimodal liquid biopsy (NVIGEN X with NERNST-Seq) at the San Antonio Breast Cancer Symposium, integrating ctDNA, CTC and protein biomarkers from one blood sample.
- **2021-12** — Presented data on highly sensitive, high-NGS-data-efficiency ctDNA testing with NVIGEN X cancer precision profiling technology.

## Links

- Website: https://nvigen.com
- LinkedIn: https://www.linkedin.com/company/nvigen-inc-
- Twitter/X: https://twitter.com/nvigen
- Facebook: https://www.facebook.com/NVIGENInc/

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Profile page: https://yespress.io/nvigen-inc
Published by YesPress — https://yespress.io
Last updated: 2026-06-13