# Khona Scientific, Inc.

> Khona Scientific is a Colorado synthetic-biology company developing BiDS, a patented platform that arranges multi-enzyme pathways inside microbial cells like molecular assembly lines. It aims to make complex, bioidentical natural compounds from sugar, selling development work, production solutions, ingredients and potentially licensed intellectual property to pharmaceutical, nutraceutical and other formulation businesses.

- **Founded:** 2019
- **Headquarters:** Lone Tree, Colorado, United States
- **Founders:** Paul Orlady (President and CEO), Jordan Buck (Chief Scientific Officer), Dylan Orlady (Chief Operating Officer)
- **Team size:** Approximately 4 employees according to supplied company data; public directories describe 1-10 employees.
- **Products:** BiDS platform, Cannabinoid biosynthesis, Process design and production solutions, Pharmaceutical KSM and API development, Bioidentical steroid hormone development
- **Notable:** U.S. Patent 11,525,148 granted in December 2022 for bidirectional multi-enzymatic scaffolds for biosynthesizing cannabinoids., Expanded into laboratory space at Hatchlabs@Wilderness Place in Boulder in November 2024., Reported acquisition of equipment enabling scale-up and optimization to 300-liter production capacity.

## Products & services

- **BiDS platform** — A patented, modular biosynthesis platform that organizes multiple enzymes into cellular assembly lines for producing complex natural compounds from simple sugar feedstocks.
- **Cannabinoid biosynthesis** — Development of fermentation pathways for non-psychoactive cannabinoid isolates including CBG, CBC and CBD families; the company reports 99%+ purity targets and no planned THC production absent regulatory change.
- **Process design and production solutions** — Proof-of-concept, pathway development, scale-up and optimization work for partners in synthetic biology and natural-product manufacturing.
- **Pharmaceutical KSM and API development** — Purpose-built biosynthetic routes for key starting materials and generic or controlled-substance active pharmaceutical ingredients, subject to validation and regulatory requirements.
- **Bioidentical steroid hormone development** — An exploratory program with EVEXIAS covering progesterone, estradiol, estrone and estriol for potential integration into hormone-therapy formulations after validation.

## Achievements

- U.S. Patent 11,525,148 granted in December 2022 for bidirectional multi-enzymatic scaffolds for biosynthesizing cannabinoids.
- Expanded into laboratory space at Hatchlabs@Wilderness Place in Boulder in November 2024.
- Reported acquisition of equipment enabling scale-up and optimization to 300-liter production capacity.
- U.S. Patent 12,385,072 granted in August 2025 for bidirectional multi-enzymatic scaffolds for biosynthesizing cannabinoids.
- Signed a letter of intent with Benuvia Operations in January 2026.
- Accepted into the BioMaP Consortium in April 2026.
- Appointed sustainable-pharmaceutical-manufacturing expert Michael A. Gonzalez, PhD, to the board in May 2026.
- Announced a focus on small-molecule pharmaceutical KSMs and APIs in July 2026.
- Signed a letter of intent with EVEXIAS in July 2026 covering four steroid hormones.

## Latest updates

- **2026-07** — Signed a letter of intent with EVEXIAS to explore production of progesterone, estradiol, estrone and estriol from renewable sugar feedstocks.
- **2026-07** — Announced a strategic focus on domestic production of small-molecule pharmaceutical key starting materials and APIs.
- **2026-07** — Bright Path highlighted Khona's investment in expanding U.S.-based KSM manufacturing.
- **2026-05** — Appointed Michael A. Gonzalez, PhD, Chief Scientific Officer of Bright Path Labs, to the board.
- **2026-04** — Announced acceptance into the BioMaP Consortium.
- **2026-01** — Signed a letter of intent with Benuvia Operations to evaluate controlled-substance API pathways.

## Links

- Website: https://khonascientific.com
- LinkedIn: https://www.linkedin.com/company/khonascientific
- Twitter/X: https://twitter.com/khonascientific
- Instagram: https://www.instagram.com/khonascientific/

---

Profile page: https://yespress.io/khona-scientific-inc
Published by YesPress — https://yespress.io
Last updated: 2026-08-21