# Jonathan Wang

> Jonathan Wang is the co-founder and CEO of Watershed (Watershed Informatics / Watershed Bio), a Cambridge-based biocomputing platform that lets biologists run complex multi-omics analyses without writing code. An MIT computer scientist who once built a high-frequency trading hedge fund out of his dorm room, Wang co-founded Domeyard before pivoting to biology in 2019, applying the speed-obsessed engineering culture of quant finance to the sprawling data problem of modern drug discovery. Watershed raised a $14.5M Series A led by Canvas Ventures in 2023 and aims to become the dominant biocomputing platform for the world's scientists.

- **Role:** Co-Founder & CEO at Watershed (Watershed Informatics / Watershed Bio)
- **Organizations:** Watershed Informatics, Domeyard LP, MIT
- **Nationality:** American
- **Education:** B.S., Electrical Engineering and Computer Science (EECS), Massachusetts Institute of Technology, M.Eng./M.S., Electrical Engineering and Computer Science (EECS), Massachusetts Institute of Technology
- **Known for:** Co-founded Domeyard, a high-frequency trading firm that at its peak was reported to make around $1 billion of trades daily, starting from an MIT dorm room., Built Domeyard's technical stack: servers colocated in Chicago Mercantile Exchange data centers, millions of lines of code, and infrastructure handling petabytes of data., Co-founded Watershed in 2019 and grew it into a multi-omics analysis platform used by biopharma discovery teams.

## Career timeline

- **2013** — Graduated MIT with a B.S. in EECS; co-founded Domeyard, a high-frequency trading hedge fund, with classmates Christina Qi and Luca Lin.
- **2015** — Completed his master's in EECS at MIT while building Domeyard's low-latency trading infrastructure as its technology lead.
- **2019** — Co-founded Watershed with longtime MIT friend Dr. Mark Kalinich to bring high-throughput computing to biology.
- **2023** — Closed a $14.5M Series A led by Canvas Ventures (March 30, 2023) with Bessemer Venture Partners and Accomplice.
- **2025** — Featured in MIT News for Watershed's no-code platform helping scientists run complex data analyses.

## Achievements

- Co-founded Domeyard, a high-frequency trading firm that at its peak was reported to make around $1 billion of trades daily, starting from an MIT dorm room.
- Built Domeyard's technical stack: servers colocated in Chicago Mercantile Exchange data centers, millions of lines of code, and infrastructure handling petabytes of data.
- Co-founded Watershed in 2019 and grew it into a multi-omics analysis platform used by biopharma discovery teams.
- Raised a $14.5M Series A in 2023, bringing total funding to roughly $18-20M across three rounds.
- Built a platform that takes scientists from sample to therapeutic insight in a single day, integrating tools like AlphaFold.

## Latest updates

- **2025-10** — Profiled in MIT News for Watershed's platform enabling scientists to run complex analyses without writing code.
- **2023-03** — Announced a $14.5M Series A led by Canvas Ventures to expand the multi-omics platform for drug discovery.

## Links

- Website: https://watershed.bio
- LinkedIn: http://www.linkedin.com/in/jonathan-wang-watershed

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Profile page: https://yespress.io/jonathan-wang
Published by YesPress — https://yespress.io
Last updated: 2026-07-01