# Jonathan Root

> Jonathan Root is a General Partner at U.S. Venture Partners (USVP) in Menlo Park, California, where he has invested in early-stage companies since 1997. A board-certified neurologist who spent nine years in clinical medicine - including as a Director of the Neurology-Neurosurgery ICU at New York Hospital-Cornell Medical Center - Root brings a rare clinician's lens to venture investing. He focuses on medical devices, biotech, and healthcare IT, with a portfolio that spans Omada Health, Carlsmed, Cleave Biosciences, and Inari Medical (acquired by Stryker in 2025). His guiding principle: 'The greatest idea in the world will not be successful if it's not practical.'

- **Role:** General Partner at U.S. Venture Partners
- **Organizations:** U.S. Venture Partners (USVP), Mission Bay Capital (advisory), National Venture Capital Association (former board director), Dartmouth Innovations Accelerator for Cancer (external review panel)
- **Nationality:** American
- **Education:** A.B. in Economics/Government, Dartmouth College, M.D., University of Florida College of Medicine, M.B.A., Columbia University School of Business
- **Known for:** General Partner at USVP since 1997 - over 28 years at the same firm, Charter member of the Ewing Marion Kauffman Fellows Program, Former board director of the National Venture Capital Association

## Career timeline

- **Pre-1995** — Practiced clinical medicine for 9 years; served as Assistant Professor of Neurology and Director of the Neurology-Neurosurgery Intensive Care Unit at The New York Hospital-Cornell Medical Center
- **1995** — Joined U.S. Venture Partners as an Ewing Marion Kauffman Fellow (charter class of the Kauffman Fellows Program)
- **1997** — Became General Partner at U.S. Venture Partners
- **2013** — Joined board of Omada Health
- **2022** — USVP raised $400M early-stage venture capital fund
- **2025** — Inari Medical, a portfolio company, acquired by Stryker Corporation

## Achievements

- General Partner at USVP since 1997 - over 28 years at the same firm
- Charter member of the Ewing Marion Kauffman Fellows Program
- Former board director of the National Venture Capital Association
- Former chairman of NVCA's Medical Industry Group
- Board member at Omada Health since 2013
- Successfully exited investments including Inari Medical (Stryker), MicroVention (Terumo), Lutonix (C.R. Bard), Cryovascular Systems (Boston Scientific), Proteolix (Onyx Pharmaceuticals), Sequent Medical (Terumo)
- Investment advisory committee member at Mission Bay Capital, UCSF
- Member of Dartmouth Innovations Accelerator for Cancer External Review Panel

## Latest updates

- **2025-02** — Portfolio company Inari Medical acquired by Stryker Corporation
- **2022-12** — USVP closed $400M early-stage venture fund

## Links

- Website: https://usvp.com/team/jon-root/
- LinkedIn: http://www.linkedin.com/in/jonathan-root-md-b3b26b56
- Twitter/X: http://www.twitter.com/USVP_
- Facebook: https://www.facebook.com/pages/US-Venture-Partners-USVP/113779035358509

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Profile page: https://yespress.io/jonathan-root
Published by YesPress — https://yespress.io
Last updated: 2026-05-18