# Instem

> Instem supplies software and expert services for life-sciences research, connecting target safety assessment, preclinical study management, laboratory workflows, regulatory data preparation and clinical trial analytics. The ARCHIMED-owned company serves more than 700 clients worldwide.

- **Founded:** 1969
- **Headquarters:** Boston, United States
- **Founders:** David Gare (Founding member of predecessor Instem Limited; former chairman)
- **Products:** Provantis, Climb, KnowledgeScan, Leadscope Model Applier, Submit
- **Notable:** More than 700 global clients reported by Instem., Completed the ARCHIMED take-private in November 2023., Acquired RockStep Solutions on 28 July 2025 and Xybion on 31 July 2025.

## Products & services

- **Provantis** — Modular preclinical study management covering design, data capture, pathology, analysis and reporting.
- **Climb** — Cloud-based management of non-GLP in vivo studies, scheduling, resources and colonies. Acquired with RockStep in 2025.
- **KnowledgeScan** — Outsourced target safety assessments combining literature mining and scientific expert review.
- **Leadscope Model Applier** — Computational toxicology predictions, expert review and reporting; numerous models developed through an FDA research collaboration.
- **Submit** — Creation and management of SEND datasets and associated submission documents.
- **SEND Advantage Services** — SEND conversion, consulting and verification services.
- **Matrix Gemini LIMS** — Configurable laboratory information management system in the Autoscribe portfolio.
- **Pristima** — Preclinical study management software acquired with Xybion in 2025.
- **Accel** — Managed cloud statistical computing environment for small and mid-sized biostatistics teams.
- **Aspire** — Cloud statistical computing environment for larger biostatistics teams.
- **Blur** — Clinical trial data and document de-identification software.
- **Instem Catalyst** — Scientific and regulatory consulting.
- **Instem Insights** — Announced September 2026; nonclinical study-data intelligence platform scheduled to launch in 2027.

## Achievements

- More than 700 global clients reported by Instem.
- Completed the ARCHIMED take-private in November 2023.
- Acquired RockStep Solutions on 28 July 2025 and Xybion on 31 July 2025.
- SRI Biosciences results reported by Instem include 15-18% lower costs and reporting times halved; customer-specific, not a general guarantee.
- Opened its global headquarters in Boston on 2 December 2025.

## Latest updates

- **2026-09** — Announced Instem Insights, scheduled to launch in 2027.
- **2026-05** — Published recap of the Boston Interact 2026 customer conference.
- **2026-03** — Announced refurbishment of the Stone UK headquarters.
- **2025-12** — Opened new Boston global headquarters.
- **2025-11** — Announced consolidation of acquired brands under Instem.

## Links

- Website: https://www.instem.com/
- LinkedIn: https://www.linkedin.com/company/instem
- Twitter/X: https://x.com/Instemsoftware
- Facebook: https://www.facebook.com/Instem.software

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Profile page: https://yespress.io/instem
Published by YesPress — https://yespress.io
Last updated: 2026-09-30