# Complete Genomics

> Complete Genomics is a San Jose-based life-science technology company and the Americas arm of MGI. Founded in 2005 as a pioneer of affordable whole-human-genome sequencing, it develops and sells next-generation sequencing instruments, reagents, and analysis software built on its proprietary PCR-free DNBSEQ (DNA nanoball) technology. The company aims to drive down the cost of sequencing - from the landmark $5,000 genome to sub-$100 - and supplies researchers, clinical labs, and biotech companies with a full workflow spanning sample prep, library construction, sequencing, and data analysis.

- **Founded:** 2005
- **Headquarters:** San Jose, California, United States
- **Founders:** Clifford Reid (Co-Founder, former Chairman, President & CEO (until 2015)), Radoje (Rade) Drmanac (Co-Founder & Chief Scientific Officer), John Curson (Co-Founder)
- **Team size:** ~260 employees
- **Products:** DNBSEQ Technology, DNBSEQ-T7, DNBSEQ-G400 / G99, DNBSEQ-T20x2, DNBSEQ-T1+
- **Notable:** Invented DNA nanoball (DNBSEQ) sequencing technology in 2005., Sequenced and published data for three complete human genomes in the journal Science (November 2009)., Drove whole-genome sequencing cost to $5,000 (2010), then $2,000 (2011).

## Products & services

- **DNBSEQ Technology** — Proprietary PCR-free next-generation sequencing chemistry based on DNA nanoballs (DNBs) generated by rolling circle replication, delivering high accuracy and low duplication rates.
- **DNBSEQ-T7** — Ultra-high-throughput sequencer aimed at large-scale genomics and population sequencing projects.
- **DNBSEQ-G400 / G99** — Flexible mid-throughput benchtop sequencers for a range of research and clinical applications.
- **DNBSEQ-T20x2** — Ultra-high-throughput system marketed as the first sequencer to bring whole-genome sequencing cost below $100.
- **DNBSEQ-T1+** — Next-generation mid-throughput sequencer completing a paired-end 150 workflow in about 24 hours at Q40 accuracy.
- **CoolMPS** — Antibody-based sequencing chemistry offering an alternative labeling approach for higher accuracy.
- **stLFR (single-tube Long Fragment Read)** — Co-barcoding technology that reconstructs long-range genomic information from short reads.
- **StereoSeq / Spatial Transcriptomics** — Spatial gene-expression platform capturing tissue-wide transcriptomes at subcellular resolution over large capture areas.
- **Reagents, kits & lab automation** — Sample extraction, library preparation kits, sequencing reagents, and automation instruments completing the end-to-end workflow.

## Achievements

- Invented DNA nanoball (DNBSEQ) sequencing technology in 2005.
- Sequenced and published data for three complete human genomes in the journal Science (November 2009).
- Drove whole-genome sequencing cost to $5,000 (2010), then $2,000 (2011).
- Completed a NASDAQ IPO in November 2010 under ticker GNOM.
- DNBSEQ-T20x2 (2023) marketed as the first sequencer to break the $100 genome barrier.
- Introduced stLFR co-barcoding and CoolMPS chemistries, and StereoSeq spatial transcriptomics.

## Latest updates

- **2025-01** — MGI Tech / Complete Genomics unveiled the DNBSEQ-T1+, a mid-throughput sequencer completing PE150 workflows in ~24 hours at Q40 accuracy.
- **2025-01** — MGI touted the world's fastest gene sequencer, targeting a genome read in around 10 minutes.
- **2023-10** — Announced next-generation sequencing platforms, including the sub-$100-genome DNBSEQ-T20x2, at the ASHG Annual Meeting.

## Links

- Website: https://completegenomics.com
- LinkedIn: https://www.linkedin.com/company/complete-genomics-inc-
- Twitter/X: https://www.twitter.com/CompleteGenomic
- Facebook: https://www.facebook.com/pages/Complete-Genomics/171211069602027

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Profile page: https://yespress.io/complete-genomics
Published by YesPress — https://yespress.io
Last updated: 2026-07-15