# Centrillion Technology

> Centrillion Technology is a Palo Alto biomolecular technology company that applies photolithography, surface chemistry and wafer-scale process control to high-density DNA chips. Its platform supports spatial biology, genotyping, pathogen genomics, custom molecular detection and exploratory long-DNA work, while its commercialization model combines product sales, custom wafer programs and licensing - most visibly through a 2023 agreement with 10x Genomics.

- **Founded:** 2009
- **Headquarters:** Palo Alto, United States
- **Founders:** Wei Zhou (Founder and Chief Executive Officer)
- **Products:** High-Density DNA Chips, Sequoia Spatial Chips, Custom ATOM Chips, Custom Genotyping Arrays, VirusHunter and Pathogen Genomics
- **Notable:** Built an integrated Palo Alto platform spanning synthesis chemistry, lithography, automation, assay workflows, scanners and data systems., Reports the ability to synthesize more than 2.4 billion distinct DNA features on one wafer., Commercialized continuous 2 µm Sequoia spatial arrays with up to 25 million features.

## Products & services

- **High-Density DNA Chips** — Photolithographically synthesized, programmable molecular surfaces with more than 2.4 billion distinct DNA features per wafer.
- **Sequoia Spatial Chips** — Commercial 5 mm × 5 mm and 10 mm × 10 mm spatial arrays with continuous 2 µm features and up to 25 million features.
- **Custom ATOM Chips** — Custom 1 mm × 1 mm chips for high-throughput focused assays; a wafer can yield approximately 5,000 chips for a current application.
- **Custom Genotyping Arrays** — Asia-Pacific arrays spanning focused or genome-wide content from 50,000 to 2 million variants per chip.
- **VirusHunter and Pathogen Genomics** — A platform developed during COVID-19 for multiplex pathogen detection, viral whole-genome readout and variant surveillance, now positioned for new collaborations.
- **Spatial Chips for Long DNA Sequencing** — A limited early-access research program using molecular zip codes to preserve long-range sequence context.
- **Custom Wafer Programs** — Selective design-to-tape-out engagements combining a partner's assay concept with Centrillion's chemistry, chip engineering and production process.

## Achievements

- Built an integrated Palo Alto platform spanning synthesis chemistry, lithography, automation, assay workflows, scanners and data systems.
- Reports the ability to synthesize more than 2.4 billion distinct DNA features on one wafer.
- Commercialized continuous 2 µm Sequoia spatial arrays with up to 25 million features.
- Licensed specified spatial and single-cell chip technology to 10x Genomics in 2023; 10x identifies an HD 3′ product as manufactured under that license.
- Developed pandemic-era VirusHunter assays for multiplex detection and SARS-CoV-2 whole-genome variant tracking.
- Received NIH/NHGRI SBIR backing for phased whole-genome sequencing via DNA barcode arrays.

## Latest updates

- **2026-09** — Current product materials list Sequoia Spatial Chips as commercially available and describe selective custom wafer programs, custom genotyping arrays and early-access long-DNA work.
- **2026-08** — The company's refreshed public positioning emphasizes high-density DNA chips as a measurement layer for biological AI.
- **2026-07** — A current recruiting page describes active focus areas including chromosome-scale DNA sequencing, next-generation genotyping and exploratory DNA computing research.
- **2023-01** — Centrillion and 10x Genomics signed a technology license and transfer agreement; 10x also acquired Centrillion's Taiwan pilot chip facility.

## Links

- Website: https://www.centrilliontech.com
- LinkedIn: https://www.linkedin.com/company/centrilliontechsiliconvalley
- Twitter/X: https://twitter.com/CentrillionBio
- Facebook: https://facebook.com/Centrillion

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Profile page: https://yespress.io/centrillion-technology
Published by YesPress — https://yespress.io
Last updated: 2026-09-26