# Calibra Scientific Inc.

> Calibra Scientific Inc. (Hangzhou Calibra Diagnostics Co., Ltd., 凯莱谱) is a clinical mass spectrometry and multi-omics company that builds the full stack of precision diagnostics - instruments, reagent kits, reference materials and central-lab services. Founded in 2016 by Hua-fen Liu, a veteran of SCIEX, Roche and Pfizer, and backed as a DIAN Diagnostics company, Calibra has launched the NMPA-registered CalQuant-S mass spectrometry system, 10+ Class II reagent kits and 300+ clinical assays, serving more than 20,000 hospitals and research institutions across China.

- **Founded:** 2016
- **Headquarters:** Hangzhou, Zhejiang, China (US office: San Jose, California)
- **Founders:** Hua-fen Liu (Founder & CEO)
- **Team size:** US-registered entity listed small (~7 on aggregators); parent operation is substantially larger as a DIAN Diagnostics company.
- **Products:** CalQuant-S, CalOmics, Clinical mass spectrometry reagent kits, Reference / standard materials, Central laboratory & multi-omics research services
- **Notable:** Launched CalQuant-S, an NMPA-registered high-end clinical mass spectrometry system (approved March 2022)., Developed 10+ NMPA Class II clinical mass spectrometry reagent kits and 300+ clinical testing assays., Published 30+ papers and expert-consensus guidelines in journals including Cell, Cell Reports and Cell Discovery.

## Products & services

- **CalQuant-S** — High-end IVD-registered clinical mass spectrometry detection system; NMPA-cleared clinical LC-MS/MS platform designed for hospital laboratories.
- **CalOmics** — Proprietary multi-omics R&D and productization platform spanning metabolomics and proteomics; supports accurate qualitative and absolute quantitative analysis of 300+ metabolites.
- **Clinical mass spectrometry reagent kits** — 10+ NMPA Class II clinical mass spectrometry reagent kits and 300+ validated clinical testing assays.
- **Reference / standard materials** — Certified reference materials and stable isotope-labeled substances for clinical mass spectrometry, following the late-2022 acquisition of Alta Scientific.
- **Central laboratory & multi-omics research services** — Medical laboratory testing services and translational multi-omics research services for hospitals and research institutions.

## Achievements

- Launched CalQuant-S, an NMPA-registered high-end clinical mass spectrometry system (approved March 2022).
- Developed 10+ NMPA Class II clinical mass spectrometry reagent kits and 300+ clinical testing assays.
- Published 30+ papers and expert-consensus guidelines in journals including Cell, Cell Reports and Cell Discovery.
- Filed 100+ invention patents, software copyrights and utility model patents.
- Serves more than 20,000 hospitals and research institutions across China.
- Founder Hua-fen Liu received AOAC International's Technical and Scientific Excellence of the Year (2015-2016) award.

## Latest updates

- **2022-03** — CalQuant-S high-end clinical mass spectrometry system receives NMPA clearance.
- **2022-05** — Closed Series B+ round of CNY 220M led by CICC Jiatai Fund.
- **2022-12** — Raised a Series C round; acquired reference-materials company Alta Scientific to bring standards in-house.

## Links

- Website: https://www.calibradx.com
- LinkedIn: https://www.linkedin.com/company/calibradx/

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Last updated: 2026-07-13