# Brian Overstreet

> Brian Overstreet is a San Francisco entrepreneur and the co-founder, president and CEO of Arbital Health, where he is building data, actuarial and AI infrastructure for managing risk-based healthcare contracts. A UC Berkeley political science graduate who began in investment banking, he previously co-founded Sagient Research Systems and Advera Health Analytics, taking both healthcare-data businesses through acquisition before returning to company-building with a deliberately chosen third act.

- **Role:** Co-Founder, President & CEO at Arbital Health
- **Organizations:** Arbital Health, Advera Health Analytics, Sagient Research Systems, Bruliam Wines, Healthy Ventures, Arietta.ai, California Business Defense, Midori Corporation
- **Education:** B.A. in Political Science, University of California, Berkeley
- **Known for:** Co-founded and led two healthcare-data companies, Sagient Research Systems and Advera Health Analytics, through acquisitions., Built Sagient research products used by pharmaceutical companies, investment firms, academic institutions and government agencies., Co-founded Arbital Health and raised $41 million across its announced Series A and Series B rounds.

## Career timeline

- **1990s** — Worked in investment banking after graduating, then moved into internet-distributed research products.
- **1999** — Co-founded Sagient Research Systems and served as president and CEO through 2009.
- **2010-2012** — Served as Sagient Research chairman until Informa acquired the company in May 2012.
- **2013-2014** — Founded and served on the board of California Business Defense, which advocated for passage of California AB 1412.
- **2010s-2022** — Co-founded and led Advera Health Analytics, whose drug-safety data and workflow business was acquired by TriNetX in 2022.
- **2023** — Co-founded Arbital Health with Travis May after a summer conversation in Palo Alto about barriers to scaling value-based care.
- **2024** — Arbital announced a $10 million Series A and acquired Santa Barbara Actuaries.
- **2025** — Arbital raised a $31 million Series B led by Valtruis, with participation from Transformation Capital, Shaper Capital and Healthy Ventures.
- **2026** — Arbital convened its second summit on risk contracting and launched Arbital Flex, a self-serve actuarial analytics product.

## Achievements

- Co-founded and led two healthcare-data companies, Sagient Research Systems and Advera Health Analytics, through acquisitions.
- Built Sagient research products used by pharmaceutical companies, investment firms, academic institutions and government agencies.
- Co-founded Arbital Health and raised $41 million across its announced Series A and Series B rounds.
- Expanded Arbital through the acquisition of Santa Barbara Actuaries and launches including Merlin AI, ATLAS and Arbital Flex.
- Founded California Business Defense, which advocated for legislation reversing a retroactive California tax and reported $120 million in savings for business founders.

## Latest updates

- **2026-07** — Arbital Health launched Arbital Flex, a self-serve product that lets organizations upload their own data and use actuarial analytics without a full platform implementation.
- **2026-03** — Overstreet hosted Arbital Health’s second summit in Nashville, bringing together more than 150 leaders focused on value-based care and risk contracting.
- **2025-10** — In a two-year company retrospective, Overstreet reported more than 50 clients, over one million patient lives represented on the platform and 270 contract adjudications.
- **2025-07** — Arbital Health announced a $31 million Series B led by Valtruis.

## Links

- Website: https://arbitalhealth.com
- LinkedIn: https://www.linkedin.com/in/brianmoverstreet
- Twitter/X: https://twitter.com/arbitalhealth

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Profile page: https://yespress.io/brian-overstreet
Published by YesPress — https://yespress.io
Last updated: 2026-08-18