# Bota Biosciences

> Bota Biosciences designs microbes, enzymes and proteins, then develops and manufactures ingredients for food, nutrition and personal care customers. Its biofoundry combines computational design, automated experiments, pilot fermentation and production, while partnerships with companies including Puratos, BASF and Syensqo bring specific ingredients to market.

- **Founded:** 2019
- **Headquarters:** Lafayette, United States; Hangzhou, China
- **Founders:** Cheryl Cui (Co-founder and CEO), Yi-Shu Tai (Co-founder and CTO), Jicong Cao (Co-founder)
- **Products:** Bota Biofoundry, Nisin, Yucca Elements, HeliaGenesis, SAION AI
- **Notable:** Built its first plasmid on the biofoundry platform in August 2020 and signed a first commercial contract that December., Opened a first manufacturing site and launched nisin in 2023., Company reports more than 1.5 million strains tested annually, more than 10,000 samples tested daily and over 4,000 liters of pilot capacity.

## Products & services

- **Bota Biofoundry** — Computational design, strain and enzyme engineering, automated screening, fermentation development and scale-up services.
- **Nisin** — Bio-preservative launched with Bota's first manufacturing site and later part of its food ingredient portfolio.
- **Yucca Elements** — Personal care ingredient business, initially including Prorylia FN, a fibronectin ingredient.
- **HeliaGenesis** — Food and nutrition ingredient brand offering biopreservatives including nisin and natamycin.
- **SAION AI** — Company-described Physical AI platform linking biological design, laboratory orchestration and execution through its Biology Protocol Language.
- **Re2 Coffea Arabica Peptide** — Coffee-ground-derived hair and scalp care bioactive distributed internationally through Syensqo.
- **SkinNexus Collag3n** — Recombinant human type III collagen fragment jointly developed with BASF for personal care; BASF markets the ingredient.
- **ZeaVida** — Precision-fermented zeaxanthin ingredient for nutrition applications.

## Achievements

- Built its first plasmid on the biofoundry platform in August 2020 and signed a first commercial contract that December.
- Opened a first manufacturing site and launched nisin in 2023.
- Company reports more than 1.5 million strains tested annually, more than 10,000 samples tested daily and over 4,000 liters of pilot capacity.
- Commercialized a biomanufacturing project with NHU in 2024.
- Developed a collagen ingredient with BASF and a coffee-derived peptide distributed by Syensqo in 2026.

## Latest updates

- **2026-09** — Joined Wageningen University-led Project SAFE, a four-year program investigating plant-derived antimicrobial ingredients and delivery systems for food preservation.
- **2026-09** — Announced a new ECM-inspired personal care ingredient under its consolidated Bota personal care business.
- **2026-08** — Described continued product application work with Proya after their 2025 strategic partnership.
- **2026-06** — BASF launched SkinNexus Collag3n, developed with Bota.
- **2026-03** — Syensqo began expanding Re2 Coffea Arabica Peptide internationally; Bota launched SAION AI.

## Links

- Website: https://bota.bio/
- LinkedIn: https://www.linkedin.com/company/botabio
- Twitter/X: https://twitter.com/bota_bio

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Profile page: https://yespress.io/bota-biosciences
Published by YesPress — https://yespress.io
Last updated: 2026-09-28