# Bexorg, Inc.

> Bexorg is a New Haven techbio company that perfuses donated, postmortem human and pig brains with custom-made artificial blood to restore their molecular and metabolic activity, turning whole organs into living-tissue testbeds for drug discovery. Its BrainEx wet-lab platform and XO Digital AI engine generate petabyte-scale human brain datasets that let pharmaceutical partners test therapies in human-relevant tissue before costly clinical trials - a direct response to the roughly 95% failure rate of central-nervous-system drugs.

- **Founded:** 2021
- **Headquarters:** New Haven, Connecticut, United States
- **Founders:** Zvonimir Vrselja (CEO & Co-founder), Nenad Sestan (Co-founder & Scientific Advisor)
- **Team size:** ~39-46 employees
- **Products:** BrainEx Platform, XO Digital
- **Notable:** Built and operates five BrainEx whole-brain perfusion machines in New Haven, with a sixth in development., Raised $42.5M total, including a $23M Series A led by Engine Ventures (October 2025)., Spun out of Nenad Sestan's Yale lab, whose 2019 Nature paper showed restored cellular activity in postmortem pig brains.

## Products & services

- **BrainEx Platform** — A proprietary whole-brain perfusion system that circulates custom artificial blood through intact postmortem human and pig brains, restoring metabolic and molecular activity so therapeutic modalities - small molecules, biologics, viral vectors, LNPs - can be delivered through the vasculature and blood-brain barrier and measured in disease-relevant states.
- **XO Digital** — An AI engine trained on petabyte-scale human brain datasets generated on BrainEx; it predicts drug responses, identifies biomarkers, and learns from each new experiment to sharpen CNS drug-discovery decisions.

## Achievements

- Built and operates five BrainEx whole-brain perfusion machines in New Haven, with a sixth in development.
- Raised $42.5M total, including a $23M Series A led by Engine Ventures (October 2025).
- Spun out of Nenad Sestan's Yale lab, whose 2019 Nature paper showed restored cellular activity in postmortem pig brains.
- Signed a multi-program drug-discovery collaboration with publicly traded Biohaven.
- Generating one of the most comprehensive human CNS datasets for AI-driven drug discovery.

## Latest updates

- **2025-10** — Announced $42.5M in total funding, including a $23M Series A led by Engine Ventures, to scale its integrated AI and whole-human brain platform.
- **2025-06** — Announced a multi-program research collaboration with Biohaven to advance next-generation CNS therapies using its whole-brain discovery platform.

## Links

- Website: https://bexorg.com
- LinkedIn: http://www.linkedin.com/company/bexorg-inc

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Profile page: https://yespress.io/bexorg-inc
Published by YesPress — https://yespress.io
Last updated: 2026-06-16